Vitamin D og type 2-diabetes

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Vitamin D and Type 2 Diabetes

Diabetes rates are increasing around the world, mainly driven by increasing levels of obesity (1). The dilemma for diabetes prevention is that the main risk factor—obesity—is a product of our modern lifestyle (the so-called obesogenic environment) (2). Immediate prospects for changing the environment to reverse rising obesity levels are not promising, and there is a need to consider other optio...

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Vitamin D Supplementation in Patients With Type 2 Diabetes: The Vitamin D for Established Type 2 Diabetes (DDM2) Study

Context Observational data support a role for vitamin D in type 2 diabetes, but evidence from trials is inconclusive. Objective To evaluate the effect of vitamin D supplementation on β-cell function and hemoglobin A1c (HbA1c) in patients with well-controlled type 2 diabetes. Design Double-blind, randomized, placebo-controlled clinical trial. Setting Tufts Medical Center, Boston, MA; VA Me...

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Vitamin D Deficiency is Associated with the Metabolic Syndrome in Subjects with Type 2 Diabetes

Background and Objectives: There is convincing evidence that subjects concomitantly affected by type 2 diabetes (T2D) and metabolic syndrome (MeS) are at greater risk for cardiovascular disease (CVD). Many metabolic derangements in T2D might be attributed to poor vitamin D status. The purpose of this study was to investigate the associations among vitamin D status, MeS and glycemic status in su...

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Focus on Vitamin D, Inflammation and Type 2 Diabetes

The initial observations linking vitamin D to type 2 diabetes in humans came from studies showing that both healthy and diabetic subjects had a seasonal variation of glycemic control. Currently, there is evidence supporting that vitamin D status is important to regulate some pathways related to type 2 diabetes development. Since the activation of inflammatory pathways interferes with normal met...

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Vitamin D Levels and Mortality in Type 2 Diabetes

OBJECTIVE To evaluate vitamin D as a predictor of all-cause and cardiovascular mortality and risk of progression to micro- or macroalbuminuria in type 2 diabetic patients. RESEARCH DESIGN AND METHODS In a longitudinal observational follow-up study, 289 type 2 diabetic patients with normoalbuminuria (n = 172), microalbuminuria (n = 73), and macroalbuminuria (n = 44) at baseline were followed f...

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ژورنال

عنوان ژورنال: Tidsskrift for Den norske legeforening

سال: 2017

ISSN: 0029-2001

DOI: 10.4045/tidsskr.16.1062